P0352 on Lexus RX
Factory diagnostic protocol and troubleshooting wire for fault code P0352 specifically for the Lexus RX (2020–2026, 2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP)).
1. Symptoms of P0352 on Lexus RX
When the Engine Control Module (ECM/PCM) on your Lexus RX (2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP)) logs fault code P0352, drivers commonly observe:
2. Most Likely Causes on Lexus RX
Historical warranty claims and technical repair bulletins for Lexus RX point to the following failure distribution:
3. Step-by-Step DIY Repair Guide for Lexus RX
Swap Coil 2 with Coil 1. If code becomes P0351, replace coil. on the Lexus RX equipped with 2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP).
Verify 12V power and trigger pulse. on the Lexus RX equipped with 2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP).
Replace Coil B with OEM part. on the Lexus RX equipped with 2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP).
Clear DTCs and confirm zero misfires. on the Lexus RX equipped with 2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP).
Equipment for Diagnosing Lexus RX (P0352)
Direct-Fit Laser Iridium Spark Plugs (Set of 4/6)
Pre-gapped iridium spark plugs engineered to restore smooth combustion on Lexus RX.
Magnetic Swivel Spark Plug Socket Set
360-degree magnetic swivel socket prevents ceramic plug cracks inside deep engine spark wells.
BlueDriver Bluetooth Pro OBDII Scan Tool
Reads and clears enhanced codes (ABS, Airbag, Transmission, Engine) & live freeze-frame telemetry on phone.
Other Common Fault Codes on Lexus RX
Frequently diagnosed powertrain, emissions, and sensor trouble codes logged on the Lexus RX:
4. Lexus RX P0352 FAQs
What causes code P0352 to trigger on a Lexus RX?
On the Lexus RX (2.4L Turbo (RX 350 275HP) / 2.5L Hybrid / 2.4L Turbo Performance Hybrid (RX 500h 366HP)), P0352 is most frequently caused by Dead Cylinder 2 ignition coil or Damaged harness wiring.
Where is the OBD-II port located on my Lexus RX?
On the Lexus RX, the 16-pin DLC diagnostic connector is located Driver footwell above brake pedal assembly. Plug in any standard OBD-II scanner with the ignition in the ON position to read freeze-frame parameters.
Can I safely drive my Lexus RX with code P0352?
No. Cylinder 2 ignition coil has failed. Given that P0352 carries a Critical severity rating, we advise avoiding heavy towing or aggressive throttle inputs until sensor readings are verified.

